An Introduction to Tissue-Biomaterial Interactions

An Introduction to Tissue-Biomaterial Interactions acquaintsan undergraduate audience with the fundamental biological processesthat influence these sophisticated, cutting-edge procedures.Chapters one through three provide more detail about themolecular-level events that happen at the tissue-implant interface,while chapters four through ten explore selected material,biological, and physiological consequences of these events. Theimportance of the body€s wound-healing response is emphasizedthroughout. Specific topics covered include:Structure andproperties of biomaterials

• Proteins
• Protein-surface interactions
• Blood-biomaterial interactions
• Inflammation and infection
• The immune system
• Biomaterial responses to implantation
• Biomaterial surface engineering
• Intimal hyperplasia and osseointegration as examples oftissue-biomaterial interactions

The text also provides extensive coverage of the three pertinentinterfaces between the body and the biomaterial, between the bodyand the living cells, and between the cells and the biomaterialthat are critical in the development of tissue-engineered productsthat incorporate living cells within a biomaterial matrix. Idealfor a one-semester, biomedical engineering course, An Introductionto Tissue-Biomaterial Interactions provides a solid framework forunderstanding today€s and tomorrow€s implantablebiomedical devices.