Handbook of Downstream Processing

Handbook of Downstream Processing

The last two decades have seen a phenomenal growth of the field of genetic or biochemical engineering and have witnessed the development and ultimately marketing of a variety of products-typically through the manipulation and growth of different types of microorganisms, followed by the recovery and purification of the associated products. The engineers and biotechnologists who are involved in the full-scale process design of such facilities must be familiar with the variety of unit operations and equipment and the applicable regulatory requirements. This book describes current commercial practice and will be useful to those engineers working in this field in the design, construction and operation of pharmaceutical and biotechnology plants. It will be of help to the chemical or pharmaceutical engineer who is developing a plant design and who faces issues such as: Should the process be batch or continuous or a combination of batch and continuous? How should the optimum process design be developed? Should one employ a new revolutionary separation which could be potentially difficult to validate or use accepted technology which involves less risk? Should the process be run with ingredients formulated from water for injection, deionized water, or even filtered tap water? Should any of the separations be run in cold rooms or in glycol jacketed lines to minimize microbial growth where sterilization is not possible? Should the process equipment and lines be designed to be sterilizedÂ in-place, cleaned-in-place, or should every piece be broken down, cleaned and autoclaved after every turn?
Country USA
Brand Springer
Manufacturer Springer
Binding Hardcover
ItemPartNumber Refer to Sapnet.
ReleaseDate 1996-10-31
UnitCount 1
EANs 9780751403640

Country	USA
Brand	Springer
Manufacturer	Springer
Binding	Hardcover
ItemPartNumber	Refer to Sapnet.
ReleaseDate	1996-10-31
UnitCount	1
EANs	9780751403640

Handbook of Downstream Processing

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